Differin Epiduo Acne Gel Treatment, Adapalene & Benzoyl Peroxide, 45g Pump | FDA-Approved OTC Acne Gel, Adapalene 0.1% + Benzoyl Peroxide 2.5%, Clears & Prevents Breakouts, Strongest OTC, 90 Day Supply
$34.99
Price: $34.99
(as of Aug 05, 2026 05:30:02 UTC – Details)
Differin Epiduo Acne Gel (90 day supply) is the most effective acne treatment approved by the FDA for use over the counter. This treatment is a prescription-strength, dual-active formula, the only OTC product combining benzoyl peroxide 2.5% and retinoid adapalene 0.1%. Uniquely engineered to amplify results. Differin Epiduo is ideal for adults with clogged pores, blackheads, whiteheads, pimples and stubborn acne. Helps treat and prevent acne and even skin tone. In one clinical study, Differin Epiduo acne skin care treatment significantly reduced total acne by 65% after 12 weeks. In the first few weeks of use, as your skin adjusts to the retinoid, you may experience dryness, redness or peeling. Some may see improvement in their acne, others may stay the same or worsen before it starts to improve. Within 4 to 12 weeks of use, users should experience fewer breakouts. Dermatologists recommend using Differin Epiduo with plenty of moisturizer as well as SPF30+ during the day. If pregnant or breastfeeding, speak with your doctor before using. Avoid waxing while using. Okay to use with other products that include hydrating, barrier repairing ingredients. Do not use with any other acne fighting ingredients like Salicylic Acid, Benzoyl peroxide, or retinols. Avoid exfoliating ingredients.
Package Dimensions : 7.09 x 2.8 x 1.77 inches; 3.21 ounces
Item model number : 0299.053340
UPC : 302994908400
Manufacturer : Galderma
ASIN : B0GSSCQ6J2
Best Sellers Rank: #9,232 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #226 in Facial Serums
Customer Reviews: 4.3 4.3 out of 5 stars (20) var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
RX STRENGTH, DUAL ACTIVE FORMULA: The most effective acne treatment approved by the FDA for use over the counter. The only OTC acne care product combining benzoyl peroxide 2.5% and retinoid adapalene 0.1% gel. FSA/HSA eligible
TREATS AND PREVENTS ACNE: Benzoyl peroxide kills bacteria from day 1 while adapalene unclogs pores and prevents future breakouts—together they help clear acne better than single-active alternatives
FOR ALL SKIN TYPES: Works for all skin tones and types, including sensitive and oily skin. Helps remove blemishes. Treats clogged pores, blackheads, whiteheads, nodules, papules, and pustules. Face acne treatment, chest acne treatment, and back acne treatment
REAL RESULTS FOR RECURRENT ACNE: In one clinical study, Differin Epiduo acne skin care treatment significantly reduced total acne by 65% after 12 weeks. Differin Epiduo treats acne, improving acne-prone skin’s overall tone, texture, and radiance
HOW TO USE: 1. Wash skin gently and pat dry. 2. Use one pump of Epiduo (a pea-sized amount) a day for your full face. 3. Moisturize after applying the gel. 4. Use SPF30+ during the day, as Differin Epiduo can make your skin more sensitive to the sun
USAGE TIPS: You can start slow by using Epiduo every other day or every third day, gradually working up to daily use. Use plenty of moisturizer and wear SPF30+ during the day. Can use morning or night
